Computational Neuroscience
Computational Neuroscience
BIO4502e.01, University of Science and Technology of China (Fall 2026)
time: 2(3,4), Week 1-18
location: Room 2307
instructor: Prof. Quan Wen
TA: Qilin Zhang
(office hours: Sat 7-8pm & by appt, LSB 205, West Campus)

prerequisites: High school knowledge of neuroscience. A good working knowledge of multivariable calculus, probability theory, linear algebra and differential equations. Familiarity of a programming language.
brief description: In this course, we will explore how physics, engineering, and mathematics have shaped our understanding of the brain. In particular, we will investigate the relationship between structure, dynamics, representation, and behavior. Special topics may include wiring optimization in neural circuit, attractor and chaotic dynamics in neural network, sensory and motor representation, biological learning rules, Hopfield network, and hierarchical control of behaviors. We will also discuss connections with modern machine learning methods.
contact:
- TA: zhangqilin8879@mail.ustc.edu.cn
- QQ group: 1092785505
discussion: Students are encouraged to post discussion on the GitHub issue page.
- Oct 15, 2026 Recitation: Sat 10/17, time 6(6,7), room 2307.
View older announcements
- Sep 23, 2026 Recitation: time 2pm room 2307.
- Sep 4, 2026 Syllabus updated.
- Aug 29, 2026 Welcome! Course homepage is live.
| Week | Date | Topic | Readings | Slides | Notes | Homework |
|---|---|---|---|---|---|---|
| W1 |
Tue 9/1 |
An introduction to computational neuroscience | Wang-Gu Model | Introduction | ||
| W2 |
Tue 9/8 |
Single neuron dynamics and computation | Single Neuron Dynamics | |||
| W3 |
Tue 9/15 |
Connecting neurons for computation | Lec 3.1 | Problem Set 1 due 9.29 | ||
| W4 |
Tue 9/22 |
Perceptron model: capacity and algorithm | Lec 3.2 | |||
|
Sun 9/27 |
Recitation: time 7(6,7) room 2307 | Rec 0 | ||||
| W5 |
Tue 9/29 |
Recurrent neural network I: from weights to dynamics | Lec 4.1 | |||
| W6 |
Tue 10/6 |
No class | ||||
|
Sat 10/10 |
Recurrent neural network II: attractor and Hopfield network | Attractors in RNN | Lec 4.2/3 | |||
| W7 |
Tue 10/13 |
Recurrent neural network III: KIMI-K3, an introduction to RMT | KIMI-K3 | Problem Set 2 due 10.19 | ||
|
Sat 10/17 |
Recitation: time 6(6,7) room 2307 | Review B-P Model MADE | Rec 1 | |||
| W8 |
Tue 10/20 |
Recurrent neural network IV: dynamical mean-field theory | Lec 4.4 | |||
| W9 |
Tue 10/27 |
Recurrent neural network V: low-rank network | Lec 4.5 | |||
| W10 |
Tue 11/3 |
Population Geometry Dimensionality | Population Geometry | Problem Set 3 due 11.10 | ||
| W11 |
Tue 11/10 |
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| W12 |
Tue 11/17 |
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| W13 |
Tue 11/24 |
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| W14 |
Tue 12/1 |
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| W15 |
Tue 12/8 |
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| W16 |
Tue 12/15 |
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| W17 |
Tue 12/22 |
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| W18 |
Tue 12/29 |